Eif2d | eukaryotic translation initiation factor 2D

GeneMGI:109342Synonyms: Lgtn, D1Ertd5e

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Behavior/neurological

16 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased exploration in new environment1 supporting datasetEif2dem1(IMPC)MbphomozygoteEarly adult7.97x10-6 
abnormal lymph node morphology1 supporting datasetEif2dem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetEif2dem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetEif2dem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetEif2dem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Eif2dem1(IMPC)MbpExon Deletionmouse

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