Eya2 | EYA transcriptional coactivator and phosphatase 2

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system

17 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes1 supporting datasetEya2em1(IMPC)MbphomozygoteEarly adultN/A * 
small spleen1 supporting datasetEya2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetEya2em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetEya2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetEya2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Eya2em1(IMPC)MbpExon Deletionmouse
Eya2tm29455(L1L2_gt0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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