Rap1gap | Rap1 GTPase-activating protein

GeneMGI:109338Synonyms: Rap1ga1, Gap, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased red blood cell distribution width1 supporting datasetRap1gapem1(IMPC)HhomozygoteEarly adult1.17x10-7 
decreased lymphocyte cell number1 supporting datasetRap1gapem1(IMPC)HhomozygoteEarly adult9.27x10-6 
increased eosinophil cell number1 supporting datasetRap1gapem1(IMPC)HhomozygoteEarly adult5.92x10-7 
increased neutrophil cell number2 supporting datasetsRap1gapem1(IMPC)HhomozygoteEarly adult3.46x10-9 
increased circulating amylase level1 supporting datasetRap1gapem1(IMPC)HhomozygoteEarly adult1.41x10-5 
increased spleen weight1 supporting datasetRap1gapem1(IMPC)HhomozygoteEarly adult2.31x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rap1gapem1(IMPC)HExon Deletionmouse
Rap1gapem2(IMPC)HExon Deletionmouse
Rap1gaptm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Rap1gaptm104784(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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