Nxn | nucleoredoxin

GeneMGI:109331Synonyms: l11Jus13

Physiological systems

24 / 24 physiological systems tested

17 Significantly impacted by the knock-out

 Immune system Endocrine/exocrine gland Integument Growth/size/body region Digestive/alimentary Muscle Hematopoietic system Craniofacial Cardiovascular system Homeostasis/metabolism Embryo Limbs/digits/tail Nervous system Vision/eye Behavior/neurological Skeleton Mortality/aging

7 No significant impact

Gene metrics:39Significant phenotypes
2Associated diseases
Expression examined in:82Adult tissues
114Embryo tissues

Phenotypes

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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Human diseases caused by Nxn mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.






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Histopathology

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IMPC related publications

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Order Mouse and ES Cells

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