Bnip1 | BCL2/adenovirus E1B interacting protein 1

GeneMGI:109328Synonyms: 5930429G21Rik, 2010005M06Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased exploration in new environment1 supporting datasetBnip1tm2b(KOMP)WtsiheterozygoteEarly adult1.39x10-7 
preweaning lethality, complete penetrance1 supporting datasetBnip1tm2b(KOMP)WtsihomozygoteEarly adultN/A * 
increased eosinophil cell number1 supporting datasetBnip1tm2b(KOMP)WtsiheterozygoteEarly adult3.13x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bnip1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Bnip1tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Bnip1tm2b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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