Bnip3 | BCL2/adenovirus E1B interacting protein 3

GeneMGI:109326Synonyms: Nip3

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Nervous system Vision/eye

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating insulin level	1 supporting dataset	Bnip3^em1(IMPC)Mbp	homozygote	Early adult	1.98x10^-7
impaired glucose tolerance	1 supporting dataset	Bnip3^em1(IMPC)Mbp	homozygote	Early adult	2.33x10^-7
absent optic nerve	1 supporting dataset	Bnip3^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal retina morphology	1 supporting dataset	Bnip3^em1(IMPC)Mbp	homozygote	Early adult	1.65x10^-5
increased circulating cholesterol level	1 supporting dataset	Bnip3^em1(IMPC)Mbp	homozygote	Early adult	9.36x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bnip3.

Associated images

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Histopathology

There is no histopathology data found for Bnip3.

IMPC related publications

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External links

No external links available for Bnip3.

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*Bnip3^em1(IMPC)Mbp*	Exon Deletion	‌	mouse

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