F7 | coagulation factor VII
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Skeleton Craniofacial Mortality/aging
12 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | F7tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased bone mineral content | 2 supporting datasets | F7tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 2.39x10-7 | ||
| decreased lean body mass | 2 supporting datasets | F7tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.63x10-12 | ||
| increased total body fat amount | 2 supporting datasets | F7tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.61x10-11 | ||
| abnormal snout morphology | 1 supporting dataset | F7tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.99x10-7 |
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External links
No external links available for F7.
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| F7tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| F7tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| F7tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |