Htr2b | 5-hydroxytryptamine (serotonin) receptor 2B

GeneMGI:109323Synonyms: 5-HT2B

Physiological systems

12 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region

10 No significant impact

12 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased total body fat amount	2 supporting datasets	Htr2b^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.55x10^-6
decreased lean body mass	1 supporting dataset	Htr2b^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	3.13x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Htr2b.

Associated images

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Histopathology

There is no histopathology data found for Htr2b.

IMPC related publications

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External links

No external links available for Htr2b.

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*Htr2b^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Htr2b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Htr2b^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Htr2b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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