Sall3 | spalt like transcription factor 3

GeneMGI:109295Synonyms: B130022O04Rik, Salt, +3 more

Physiological systems

24 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

15 No significant impact

Gene metrics:15Significant phenotypes
0Associated diseases
Expression examined in:78Adult tissues
27Embryo tissues

Phenotypes

abnormal thymus morphology1 supporting datasetSall3tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetSall3tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
hyperactivity2 supporting datasetsSall3tm1.1(KOMP)MbpheterozygoteEarly adult3.06x10-5 
abnormal heart morphology1 supporting datasetSall3tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
abnormal skin morphology1 supporting datasetSall3tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
enlarged testis1 supporting datasetSall3tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetSall3tm1.1(KOMP)MbphomozygoteEarly adultN/A * 
enlarged heart1 supporting datasetSall3tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetSall3tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
small testis1 supporting datasetSall3tm1.1(KOMP)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sall3tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
mouse
Sall3tm1.1(KOMP)MbpReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Sall3tm460723(Ifitm2_intron_L1L2_GT2_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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