Nnt | nicotinamide nucleotide transhydrogenase

GeneMGI:109279Synonyms: 4930423F13Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating glucose level1 supporting datasetNntem1(IMPC)HhomozygoteEarly adult4.81x10-7 
abnormal gait1 supporting datasetNntem1(IMPC)HhomozygoteEarly adult1.31x10-7 
increased circulating cholesterol level1 supporting datasetNntem1(IMPC)HhomozygoteEarly adult9.1x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nntem1(IMPC)HExon Deletionmouse
Nnttm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nnttm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Nnttm41840(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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