Tead3 | TEA domain family member 3
Physiological systems
18 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Skeleton
16 No significant impact
6 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased circulating serum albumin level | 1 supporting dataset | Tead3tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.82x10-5 | ||
| decreased bone trabecula number | 1 supporting dataset | Tead3tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.12x10-5 | ||
| increased circulating magnesium level | 1 supporting dataset | Tead3tm1a(EUCOMM)Wtsi | homozygote | Early adult | 4.49x10-5 | ||
| increased bone trabecular spacing | 1 supporting dataset | Tead3tm1a(EUCOMM)Wtsi | homozygote | Early adult | 2.31x10-10 | ||
| increased circulating creatinine level | 1 supporting dataset | Tead3tm1a(EUCOMM)Wtsi | homozygote | Early adult | 5.92x10-5 |
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Human diseases caused by Tead3 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Tead3.
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| Tead3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Tead3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Tead3tm83926(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |