Ccn3 | cellular communication network factor 3

GeneMGI:109185Synonyms: C130088N23Rik, CCN3, +1 more

Physiological systems

20 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Growth/size/body region Vision/eye Liver/biliary system Hematopoietic system Renal/urinary system

14 No significant impact

4 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetCcn3em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal spleen morphology1 supporting datasetCcn3em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal liver morphology1 supporting datasetCcn3em1(IMPC)MbphomozygoteLate adultN/A * 
anophthalmia1 supporting datasetCcn3em1(IMPC)MbphomozygoteLate adultN/A * 
small spleen2 supporting datasetsCcn3em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetCcn3em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal vitreous body morphology1 supporting datasetCcn3em1(IMPC)MbphomozygoteLate adult6.56x10-5 
enlarged kidney1 supporting datasetCcn3em1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ccn3em1(IMPC)MbpExon Deletionmouse
Ccn3tm51069(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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