Taf6 | TATA-box binding protein associated factor 6

GeneMGI:109129Synonyms: p80, 80kDa, +1 more

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Mortality/aging

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:51Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased circulating aspartate transaminase level	1 supporting dataset	Taf6^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.56x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Taf6^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Taf6^{tm1b(EUCOMM)Hmgu}	homozygote	E9.5	N/A ^*
decreased total retina thickness	1 supporting dataset	Taf6^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.82x10^-5
decreased circulating serum albumin level	1 supporting dataset	Taf6^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.64x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Taf6.

Associated images

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Histopathology

There is no histopathology data found for Taf6.

IMPC related publications

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External links

No external links available for Taf6.

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*Taf6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Taf6^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Taf6^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Taf6^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Taf6^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Taf6^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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