Timp4 | tissue inhibitor of metalloproteinase 4
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Integument Nervous system Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system
13 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal skin morphology | 1 supporting dataset | Timp4em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| absent optic nerve | 1 supporting dataset | Timp4em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small kidney | 1 supporting dataset | Timp4em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| small spleen | 1 supporting dataset | Timp4em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| increased startle reflex | 1 supporting dataset | Timp4em1(IMPC)Mbp | homozygote | Early adult | 2.56x10-5 | ||
| increased freezing behavior | 1 supporting dataset | Timp4em1(IMPC)Mbp | homozygote | Early adult | 2.84x10-7 |
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External links
No external links available for Timp4.
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| Timp4em1(IMPC)Mbp | Exon Deletion | | mouse |
| Timp4tm197186(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |