Nbr1 | NBR1, autophagy cargo receptor

GeneMGI:108498

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes



impaired glucose tolerance	1 supporting dataset		Nbr1^{tm1b(KOMP)Wtsi}	homozygote	Early adult		7.42x10^-18

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nbr1.

Associated images

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Histopathology

There is no histopathology data found for Nbr1.

IMPC related publications

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External links

No external links available for Nbr1.

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*Nbr1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Nbr1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Nbr1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Nbr1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Nbr1^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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