Kcnj12 | potassium inwardly-rectifying channel, subfamily J, member 12

GeneMGI:108495Synonyms: MB-IRK2, IRK2, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased hematocrit1 supporting datasetKcnj12tm1a(EUCOMM)WtsihomozygoteEarly adult2x10-5 
increased startle reflex1 supporting datasetKcnj12tm1a(EUCOMM)WtsihomozygoteEarly adult2.14x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kcnj12tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Kcnj12tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Kcnj12tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Kcnj12tm3a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Kcnj12tm3e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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