Tcf20 | transcription factor 20

GeneMGI:108399Synonyms: 2810438H08Rik, SPBP, +1 more

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Skeleton

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating creatine kinase level	1 supporting dataset	Tcf20^{em1(IMPC)Wtsi}	homozygote	Early adult	3.26x10^-6
increased circulating insulin level	1 supporting dataset	Tcf20^{em1(IMPC)Wtsi}	homozygote	Early adult	5x10^-24
decreased body length	1 supporting dataset	Tcf20^{em1(IMPC)Wtsi}	homozygote	Early adult	1.76x10^-6
increased total body fat amount	1 supporting dataset	Tcf20^{em1(IMPC)Wtsi}	homozygote	Early adult	1.97x10^-6
decreased bone mineral content	1 supporting dataset	Tcf20^{em1(IMPC)Wtsi}	homozygote	Early adult	1.62x10^-7
decreased lean body mass	1 supporting dataset	Tcf20^{em1(IMPC)Wtsi}	homozygote	Early adult	1.53x10^-7
increased circulating alkaline phosphatase level	1 supporting dataset	Tcf20^{em1(IMPC)Wtsi}	homozygote	Early adult	2.58x10^-7
increased circulating aspartate transaminase level	1 supporting dataset	Tcf20^{em1(IMPC)Wtsi}	homozygote	Early adult	7.81x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tcf20.

Associated images

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Histopathology

There is no histopathology data found for Tcf20.

IMPC related publications

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External links

No external links available for Tcf20.

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*Tcf20^{em1(IMPC)Wtsi}*	Deletion	‌	mouse
*Tcf20^{em2(IMPC)Wtsi}*	Exon Deletion	‌	mouse

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