Prkg1 | protein kinase, cGMP-dependent, type I
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Growth/size/body region Digestive/alimentary Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system
13 No significant impact
4 Not tested
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| enlarged heart | 1 supporting dataset | Prkg1tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| enlarged spleen | 1 supporting dataset | Prkg1tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal duodenum morphology | 1 supporting dataset | Prkg1tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Prkg1tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased startle reflex | 1 supporting dataset | Prkg1tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.69x10-7 |
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External links
No external links available for Prkg1.
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| Prkg1tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector es cell |
| Prkg1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Prkg1tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Prkg1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |