Cep250 | centrosomal protein 250

GeneMGI:108084Synonyms: Inmp, Cep2, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Reproductive system Adipose tissue Hearing/vestibular/ear Behavior/neurological

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased total body fat amount	1 supporting dataset	Cep250^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.26x10^-6
abnormal auditory brainstem response	2 supporting datasets	Cep250^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.94x10^-10
absent pinna reflex	1 supporting dataset	Cep250^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.03x10^-7
male infertility	1 supporting dataset	Cep250^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cep250.

Associated images

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Histopathology

There is no histopathology data found for Cep250.

IMPC related publications

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External links

No external links available for Cep250.

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*Cep250^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cep250^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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