Traf6 | TNF receptor-associated factor 6

GeneMGI:108072Synonyms: C630032O20Rik, 2310003F17Rik

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased grip strength	2 supporting datasets	Traf6^{tm2a(EUCOMM)Wtsi}	heterozygote	Early adult	1.86x10^-7
preweaning lethality, complete penetrance	1 supporting dataset	Traf6^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Traf6.

Associated images

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Histopathology

There is no histopathology data found for Traf6.

IMPC related publications

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External links

No external links available for Traf6.

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*Traf6^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Traf6^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Traf6^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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