Wnt10a | wingless-type MMTV integration site family, member 10A

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Pigmentation Integument Adipose tissue Limbs/digits/tail Skeleton

16 No significant impact

3 Not tested

Gene metrics:5Significant phenotypes
7Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

short tibia1 supporting datasetWnt10atm1.1(KOMP)VlcghomozygoteEarly adult8.27x10-6 
abnormal coat/ hair morphology3 supporting datasetsWnt10atm1.1(KOMP)VlcghomozygoteEarly adult1.77x10-7 
decreased total body fat amount1 supporting datasetWnt10atm1.1(KOMP)VlcghomozygoteEarly adult4.84x10-5 
abnormal coat/hair pigmentation1 supporting datasetWnt10atm1.1(KOMP)VlcghomozygoteEarly adult1.88x10-9 
increased bone mineral content1 supporting datasetWnt10atm1.1(KOMP)VlcghomozygoteEarly adult8.14x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wnt10atm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Wnt10atm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Wnt10atm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Wnt10atm40045(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Wnt10atm40045(L1L2_st2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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