Nobox | NOBOX oogenesis homeobox
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Embryo Growth/size/body region Behavior/neurological Mortality/aging
13 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
1Associated diseases
Expression examined in:42Adult tissues
29Embryo tissues
| abnormal embryo size | 1 supporting dataset | Noboxtm1.1(KOMP)Vlcg | heterozygote | E9.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Noboxtm1.1(KOMP)Vlcg | heterozygote | E9.5 | N/A * | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Noboxtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| hyperactivity | 1 supporting dataset | Noboxtm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.95x10-8 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Noboxtm1.1(KOMP)Vlcg | heterozygote | Early adult | 8.1x10-5 | ||
| abnormal seminal vesicle morphology | 1 supporting dataset | Noboxtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * |
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| Noboxtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Noboxtm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Noboxtm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Noboxtm2a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |