Slc8a3 | solute carrier family 8 (sodium/calcium exchanger), member 3

GeneMGI:107976Synonyms: Ncx3

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

44Embryo tissues

Phenotypes

Phy. System:



increased circulating sodium level	1 supporting dataset	Slc8a3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.01x10^-8
increased circulating alkaline phosphatase level	1 supporting dataset	Slc8a3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.79x10^-15
abnormal sleep behavior	1 supporting dataset	Slc8a3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.18x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Slc8a3.

Associated images

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Histopathology

There is no histopathology data found for Slc8a3.

IMPC related publications

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External links

No external links available for Slc8a3.

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*Slc8a3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Slc8a3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Slc8a3^{tm464123(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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