Klc2 | kinesin light chain 2

GeneMGI:107953Synonyms: 8030455F02Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response6 supporting datasetsKlc2tm1e(EUCOMM)WtsihomozygoteEarly adult1.11x10-18 
absent pinna reflex1 supporting datasetKlc2tm1e(EUCOMM)WtsihomozygoteEarly adult2.37x10-15 
increased circulating free fatty acids level1 supporting datasetKlc2tm1e(EUCOMM)WtsihomozygoteEarly adult5.91x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Klc2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Klc2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Klc2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
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