Ezh2 | enhancer of zeste 2 polycomb repressive complex 2 subunit

GeneMGI:107940Synonyms: Enx1h, Enx-1, +1 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Skeleton

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating triglyceride level	1 supporting dataset	Ezh2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.75x10^-8
increased lumbar vertebrae number	1 supporting dataset	Ezh2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.9x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ezh2.

Associated images

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Histopathology

There is no histopathology data found for Ezh2.

IMPC related publications

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External links

No external links available for Ezh2.

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*Ezh2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Ezh2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ezh2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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