Prmt1 | protein arginine N-methyltransferase 1

GeneMGI:107846Synonyms: Hrmt1l2, 6720434D09Rik

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



limb grasping	1 supporting dataset	Prmt1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.42x10^-5
decreased circulating glycerol level	1 supporting dataset	Prmt1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.6x10^-5
preweaning lethality, complete penetrance	2 supporting datasets	Prmt1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating total protein level	1 supporting dataset	Prmt1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.98x10^-5
increased circulating alkaline phosphatase level	1 supporting dataset	Prmt1^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.3x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Prmt1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Prmt1.

IMPC related publications

Loading...

External links

No external links available for Prmt1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Prmt1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Prmt1^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse

My Genes