Uqcrq | ubiquinol-cytochrome c reductase, complex III subunit VII

GeneMGI:107807Synonyms: Qpc, QP-C, +4 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Mortality/aging

15 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
21Embryo tissues

Phenotypes

embryonic lethality prior to tooth bud stage1 supporting datasetUqcrqtm1b(EUCOMM)HmguhomozygoteE12.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetUqcrqtm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
decreased mean platelet volume1 supporting datasetUqcrqtm1b(EUCOMM)HmguheterozygoteEarly adult4.19x10-10 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Uqcrqtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Uqcrqtm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
es cell
Uqcrqtm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Uqcrqtm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse

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