Lhx5 | LIM homeobox protein 5

GeneMGI:107792Synonyms: Lim2

Physiological systems

23 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Cardiovascular system Mortality/aging Craniofacial

13 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:12Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged thymus2 supporting datasetsLhx5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
small seminal vesicle1 supporting datasetLhx5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal heart morphology1 supporting datasetLhx5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal thymus morphology2 supporting datasetsLhx5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
increased leukocyte cell number1 supporting datasetLhx5em1(IMPC)CcpczheterozygoteEarly adult1.13x10-5 
abnormal spleen morphology1 supporting datasetLhx5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetLhx5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal tooth morphology1 supporting datasetLhx5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetLhx5em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetLhx5em1(IMPC)CcpczheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lhx5em1(IMPC)CcpczExon Deletionmouse

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