Neurod2 | neurogenic differentiation 2

GeneMGI:107755Synonyms: Ndrf, bHLHa1

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Limbs/digits/tail Nervous system Vision/eye Behavior/neurological Skeleton

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:23Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased food intake	1 supporting dataset	Neurod2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.41x10^-9
abnormal coat appearance	2 supporting datasets	Neurod2^{em1(IMPC)Hmgu}	heterozygote	Early adult	5.52x10^-5
narrow eye opening	1 supporting dataset	Neurod2^{em1(IMPC)Hmgu}	heterozygote	Early adult	2.26x10^-5
hyperactivity	6 supporting datasets	Neurod2^{em1(IMPC)Hmgu}	homozygote	Early adult	4.1x10^-45
cornea deposits	1 supporting dataset	Neurod2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.46x10^-12
decreased vertical activity	1 supporting dataset	Neurod2^{em1(IMPC)Hmgu}	homozygote	Early adult	6.19x10^-5
increased anxiety-related response	1 supporting dataset	Neurod2^{em1(IMPC)Hmgu}	homozygote	Early adult	2.44x10^-6
abnormal retina morphology	1 supporting dataset	Neurod2^{em1(IMPC)Hmgu}	homozygote	Early adult	3.93x10^-12
narrow eye opening	1 supporting dataset	Neurod2^{em1(IMPC)Hmgu}	homozygote	Early adult	2x10^-11
increased thigmotaxis	2 supporting datasets	Neurod2^{em1(IMPC)Hmgu}	homozygote	Early adult	1.35x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Neurod2.

Associated images

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Histopathology

There is no histopathology data found for Neurod2.

IMPC related publications

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External links

No external links available for Neurod2.

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*Neurod2^{em1(IMPC)Hmgu}*	Intra-exon deletion	‌	mouse
*Neurod2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Neurod2^{tm1.1(EGFP_CreERT2)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	es cell
*Neurod2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Neurod2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Neurod2^{tm51163(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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