Pvr | poliovirus receptor

GeneMGI:107741Synonyms: mE4, D7Ertd458e, +5 more

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Skeleton Craniofacial

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating insulin level1 supporting datasetPvrem1(IMPC)WtsihomozygoteEarly adult7.75x10-15 
abnormal incisor morphology1 supporting datasetPvrem1(IMPC)WtsihomozygoteEarly adult9.18x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pvrem1(IMPC)WtsiDeletionmouse
Pvrtm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Pvrtm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Pvrtm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Pvrtm2e(KOMP)WtsiTargeted, non-conditional allelees cell

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