Myo7b | myosin VIIB

GeneMGI:107709

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:52Adult tissues

50Embryo tissues

Phenotypes



increased circulating sodium level	1 supporting dataset	Myo7b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	3.65x10^-14
decreased circulating glucose level	1 supporting dataset	Myo7b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	7.26x10^-5
increased circulating chloride level	1 supporting dataset	Myo7b^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	1.17x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Myo7b.

Associated images

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Histopathology

There is no histopathology data found for Myo7b.

IMPC related publications

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External links

No external links available for Myo7b.

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*Myo7b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Myo7b^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Myo7b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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