Zfp462 | zinc finger protein 462
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Embryo Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging
13 No significant impact
4 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
preweaning lethality, complete penetrance | 3 supporting datasets | Zfp462em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
decreased lean body mass | 2 supporting datasets | Zfp462em1(IMPC)Tcp | heterozygote | Early adult | 1.14x10-10 | ||
thrombocytopenia | 1 supporting dataset | Zfp462em1(IMPC)Tcp | heterozygote | Early adult | 5.71x10-8 | ||
edema | 1 supporting dataset | Zfp462em1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
increased startle reflex | 1 supporting dataset | Zfp462em1(IMPC)Tcp | heterozygote | Early adult | 1.24x10-7 | ||
increased total body fat amount | 2 supporting datasets | Zfp462em1(IMPC)Tcp | heterozygote | Early adult | 2.34x10-7 | ||
impaired glucose tolerance | 1 supporting dataset | Zfp462em1(IMPC)Tcp | heterozygote | Early adult | 3.4x10-5 | ||
abnormal embryo size | 1 supporting dataset | Zfp462em1(IMPC)Tcp | homozygote | E15.5 | N/A * |
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External links
No external links available for Zfp462.
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Zfp462em1(IMPC)Tcp | Intra-exon deletion | | mouse |
Zfp462tm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
Zfp462tm459785(Ifitm2_intron_L1L2_GT1_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Zfp462tm459827(L1L2_GT2_LF2A_LacZ_BetactP_neo) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |