Kif3b | kinesin family member 3B

GeneMGI:107688

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Behavior/neurological Skeleton Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased bone mineral content	1 supporting dataset	Kif3b^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	9.12x10^-5
prenatal lethality prior to heart atrial septation	1 supporting dataset	Kif3b^{tm1b(EUCOMM)Wtsi}	homozygote	E15.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Kif3b^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased grip strength	2 supporting datasets	Kif3b^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.62x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kif3b.

Associated images

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Histopathology

There is no histopathology data found for Kif3b.

IMPC related publications

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External links

No external links available for Kif3b.

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*Kif3b^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Kif3b^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Kif3b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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