Akr1b8 | aldo-keto reductase family 1, member B8
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
15 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues
| increased grip strength | 4 supporting datasets | Akr1b8tm1.1(KOMP)Vlcg | homozygote | Early adult | 2.4x10-15 | ||
| increased circulating total protein level | 1 supporting dataset | Akr1b8tm1.1(KOMP)Vlcg | homozygote | Early adult | 8.94x10-5 | ||
| decreased circulating glucose level | 1 supporting dataset | Akr1b8tm1.1(KOMP)Vlcg | homozygote | Early adult | 4.07x10-6 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Akr1b8tm1.1(KOMP)Vlcg | homozygote | Early adult | 5.36x10-6 |
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External links
No external links available for Akr1b8.
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| Akr1b8tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Akr1b8tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Akr1b8tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Akr1b8tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |