Ifnar1 | interferon (alpha and beta) receptor 1

GeneMGI:107658Synonyms: Ifar, IFN-alpha/betaR, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Integument Hematopoietic system Skeleton

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased circulating amylase level	1 supporting dataset	Ifnar1^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	4.76x10^-10
increased circulating creatinine level	1 supporting dataset	Ifnar1^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	4.32x10^-7
abnormal vibrissa morphology	1 supporting dataset	Ifnar1^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	6.98x10^-5
increased bone mineral content	1 supporting dataset	Ifnar1^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	6.71x10^-5
improved glucose tolerance	1 supporting dataset	Ifnar1^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	1.16x10^-6
decreased KLRG1-positive NK cell number	1 supporting dataset	Ifnar1^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased monocyte cell number	1 supporting dataset	Ifnar1^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased circulating fructosamine level	1 supporting dataset	Ifnar1^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	8.09x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ifnar1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ifnar1.

IMPC related publications

Loading...

External links

No external links available for Ifnar1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ifnar1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Ifnar1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse

My Genes