Wbp1l | WW domain binding protein 1 like

GeneMGI:107577Synonyms: D19Wsu162e

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Integument Nervous system Vision/eye Behavior/neurological Cardiovascular system

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:12Significant phenotypes

0Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating total protein level	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	3.08x10^-5
abnormal eye anterior chamber depth	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	1.02x10^-7
decreased circulating alkaline phosphatase level	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	1.45x10^-17
prolonged RR interval	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	3.8x10^-6
decreased circulating serum albumin level	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	2.09x10^-7
decreased prepulse inhibition	4 supporting datasets	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	3.25x10^-22
decreased circulating calcium level	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	6.07x10^-9
abnormal skin coloration	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	9.79x10^-7
decreased heart rate	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	2.42x10^-5
increased startle reflex	1 supporting dataset	Wbp1l^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	2.55x10^-20

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Wbp1l.

Associated images

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Histopathology

There is no histopathology data found for Wbp1l.

IMPC related publications

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External links

No external links available for Wbp1l.

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*Wbp1l^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Wbp1l^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Wbp1l^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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