Sema5b | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B

GeneMGI:107555Synonyms: SemG, Semag

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Hematopoietic system Behavior/neurological Skeleton

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased hematocrit1 supporting datasetSema5btm1a(EUCOMM)WtsihomozygoteEarly adult4.39x10-5 
increased startle reflex5 supporting datasetsSema5btm1a(EUCOMM)WtsihomozygoteEarly adult1.58x10-6 
decreased bone mineral density1 supporting datasetSema5btm1a(EUCOMM)WtsihomozygoteEarly adult4.67x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Sema5btm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Sema5btm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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