Rgl1 | ral guanine nucleotide dissociation stimulator,-like 1

GeneMGI:107484Synonyms: Rgl

Physiological systems

22 / 24 physiological systems tested

16 Significantly impacted by the knock-out

Reproductive system Immune system Growth/size/body region Digestive/alimentary Hematopoietic system Craniofacial Cardiovascular system Renal/urinary system Homeostasis/metabolism Embryo Limbs/digits/tail Nervous system Vision/eye Liver/biliary system Behavior/neurological Mortality/aging

6 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:32Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



enlarged spleen	2 supporting datasets	Rgl1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
cleft palate	1 supporting dataset	Rgl1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
small liver	2 supporting datasets	Rgl1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
decreased prepulse inhibition	3 supporting datasets	Rgl1^em1(IMPC)Mbp	heterozygote	Early adult	5.09x10^-7
enlarged lymph nodes	2 supporting datasets	Rgl1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal lymph node morphology	2 supporting datasets	Rgl1^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal midbrain development	1 supporting dataset	Rgl1^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Rgl1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
increased neutrophil cell number	2 supporting datasets	Rgl1^em1(IMPC)Mbp	heterozygote	Early adult	3.04x10^-6
edema	1 supporting dataset	Rgl1^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rgl1.

Associated images

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Histopathology

There is no histopathology data found for Rgl1.

IMPC related publications

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External links

No external links available for Rgl1.

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*Rgl1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Rgl1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rgl1^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Rgl1^{tm2a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Rgl1^{tm2e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Rgl1^{tm41618(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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