Cd38 | CD38 antigen

GeneMGI:107474Synonyms: Cd38-rs1

Physiological systems

22 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system

18 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased memory-marker CD4-positive NK T cell number	1 supporting dataset	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.48x10^-10
abnormal spleen morphology	2 supporting datasets	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased T-helper cell number	1 supporting dataset	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	2.42x10^-5
abnormal thymus morphology	1 supporting dataset	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged spleen	2 supporting datasets	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
decreased CD4-positive NK T cell number	1 supporting dataset	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.28x10^-10
increased effector memory CD8-positive, alpha-beta T cell number	1 supporting dataset	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.76x10^-5
decreased NK T cell number	1 supporting dataset	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.63x10^-9
decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number	1 supporting dataset	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	4.52x10^-20
decreased CD4-positive, alpha-beta T cell number	1 supporting dataset	Cd38^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.03x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Cd38.

Associated images

Loading...

Histopathology

There is no histopathology data found for Cd38.

IMPC related publications

Loading...

External links

No external links available for Cd38.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Cd38^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Cd38^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Cd38^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Cd38^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes