Cox6b1 | cytochrome c oxidase, subunit 6B1
Physiological systems
21 / 24 physiological systems tested
9 Significantly impacted by the knock-out
Immune system Integument Endocrine/exocrine gland Embryo Growth/size/body region Vision/eye Hematopoietic system Cardiovascular system Mortality/aging
12 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Cox6b1em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Cox6b1em1(IMPC)Tcp | homozygote | E12.5 | N/A * | ||
| abnormal sinus arrhythmia | 1 supporting dataset | Cox6b1em1(IMPC)Tcp | heterozygote | Early adult | 1.13x10-8 | ||
| absent adrenal gland | 1 supporting dataset | Cox6b1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| increased spleen weight | 1 supporting dataset | Cox6b1em1(IMPC)Tcp | heterozygote | Early adult | 8.62x10-5 | ||
| abnormal skin morphology | 1 supporting dataset | Cox6b1em1(IMPC)Tcp | heterozygote | Early adult | N/A * | ||
| microphthalmia | 1 supporting dataset | Cox6b1em1(IMPC)Tcp | homozygote | E12.5 | N/A * |
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External links
No external links available for Cox6b1.
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| Cox6b1em1(IMPC)Tcp | Exon Deletion | | mouse |
| Cox6b1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Cox6b1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |