Ube2i | ubiquitin-conjugating enzyme E2I

GeneMGI:107365Synonyms: UBC9, 5830467E05Rik, +2 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Ube2i^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased mean corpuscular hemoglobin	1 supporting dataset	Ube2i^em1(IMPC)J	heterozygote	Early adult	3.55x10^-19
increased leukocyte cell number	1 supporting dataset	Ube2i^em1(IMPC)J	heterozygote	Early adult	3.93x10^-10
abnormal vocalization	1 supporting dataset	Ube2i^em1(IMPC)J	heterozygote	Early adult	2.42x10^-10
increased mean corpuscular volume	1 supporting dataset	Ube2i^em1(IMPC)J	heterozygote	Early adult	1.36x10^-15
embryonic lethality prior to organogenesis	1 supporting dataset	Ube2i^em1(IMPC)J	homozygote	E9.5	N/A ^*
increased circulating phosphate level	1 supporting dataset	Ube2i^em1(IMPC)J	heterozygote	Early adult	9.3x10^-5
abnormal locomotor behavior	1 supporting dataset	Ube2i^em1(IMPC)J	heterozygote	Early adult	9.64x10^-5
decreased erythrocyte cell number	1 supporting dataset	Ube2i^em1(IMPC)J	heterozygote	Early adult	5.98x10^-6
increased circulating calcium level	1 supporting dataset	Ube2i^em1(IMPC)J	heterozygote	Early adult	9.56x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ube2i.

Associated images

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Histopathology

There is no histopathology data found for Ube2i.

IMPC related publications

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External links

No external links available for Ube2i.

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*Ube2i^em1(IMPC)J*	Exon Deletion	‌	mouse
*Ube2i^{tm85581(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Ube2i^{tm85581(L1L2_Pgk_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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