Il17a | interleukin 17A
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Growth/size/body region Liver/biliary system Hematopoietic system Behavior/neurological Renal/urinary system
14 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
abnormal spleen morphology | 1 supporting dataset | Il17aem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
small liver | 1 supporting dataset | Il17aem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
increased freezing behavior | 1 supporting dataset | Il17aem1(IMPC)Mbp | homozygote | Early adult | 1.03x10-9 | ||
small kidney | 1 supporting dataset | Il17aem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal kidney morphology | 1 supporting dataset | Il17aem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal liver morphology | 1 supporting dataset | Il17aem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
enlarged spleen | 1 supporting dataset | Il17aem1(IMPC)Mbp | homozygote | Early adult | N/A * |
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External links
No external links available for Il17a.
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Il17aem1(IMPC)Mbp | Exon Deletion | | mouse |
Il17atm88656(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |