Man2b1 | mannosidase 2, alpha B1

GeneMGI:107286Synonyms: lysosomal alpha-mannosidase

Physiological systems

10 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Behavior/neurological

9 No significant impact

14 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:1Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased locomotor activity2 supporting datasetsMan2b1em1(IMPC)HhomozygoteEarly adult4.58x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Man2b1em1(IMPC)HInter-exon deletionmouse
Man2b1tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Man2b1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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