Cpd | carboxypeptidase D

GeneMGI:107265Synonyms: D830034L15Rik

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Embryo Growth/size/body region Mortality/aging Cardiovascular system

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetCpdem1(IMPC)JhomozygoteEarly adultN/A * 
impaired glucose tolerance1 supporting datasetCpdem1(IMPC)JheterozygoteEarly adult2.49x10-6 
pallor1 supporting datasetCpdem1(IMPC)JhomozygoteE18.5N/A * 
increased circulating aspartate transaminase level1 supporting datasetCpdem1(IMPC)JheterozygoteEarly adult1.07x10-6 
abnormal embryo size1 supporting datasetCpdem1(IMPC)JhomozygoteE18.5N/A * 
prolonged QRS complex duration1 supporting datasetCpdem1(IMPC)JheterozygoteEarly adult5.24x10-5 
abnormal cholesterol homeostasis1 supporting datasetCpdem1(IMPC)JheterozygoteEarly adult5.83x10-6 
increased circulating creatinine level1 supporting datasetCpdem1(IMPC)JheterozygoteEarly adult3.63x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cpdem1(IMPC)JExon Deletionmouse

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