Nsun2 | NOL1/NOP2/Sun domain family member 2

GeneMGI:107252Synonyms: Misu

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Growth/size/body region Limbs/digits/tail Vision/eye Behavior/neurological Skeleton Craniofacial Mortality/aging

13 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:16Significant phenotypes

3Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal joint morphology	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.18x10^-5
abnormal gait	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.94x10^-5
abnormal humerus morphology	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.08x10^-5
abnormal response to new environment	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.08x10^-5
decreased body weight	3 supporting datasets	Nsun2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	0
abnormal cranium morphology	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.13x10^-6
abnormal gait	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.53x10^-5
abnormal snout morphology	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	3.37x10^-5
abnormal eye size	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.11x10^-5
abnormal tooth morphology	1 supporting dataset	Nsun2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.39x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nsun2.

Associated images

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Histopathology

There is no histopathology data found for Nsun2.

IMPC related publications

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External links

No external links available for Nsun2.

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*Nsun2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Nsun2^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Nsun2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Nsun2^{tm42933(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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