Bmpr1b | bone morphogenetic protein receptor, type 1B

GeneMGI:107191Synonyms: BMPR-IB, Alk6, +2 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Limbs/digits/tail Nervous system Vision/eye Liver/biliary system Behavior/neurological Skeleton

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:17Significant phenotypes

8Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	4 supporting datasets	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	3.51x10^-83
small seminal vesicle	1 supporting dataset	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal vitreous body morphology	1 supporting dataset	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	6.32x10^-6
abnormal liver morphology	1 supporting dataset	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
increased freezing behavior	1 supporting dataset	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	7.8x10^-15
abnormal optic disk morphology	1 supporting dataset	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	5.18x10^-17
abnormal bone structure	1 supporting dataset	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	4.15x10^-7
abnormal testis morphology	1 supporting dataset	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal autopod morphology	2 supporting datasets	Bmpr1b^em1(IMPC)Mbp	homozygote	Early adult	2.72x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Bmpr1b.

Associated images

Loading...

Histopathology

There is no histopathology data found for Bmpr1b.

IMPC related publications

Loading...

External links

No external links available for Bmpr1b.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Bmpr1b^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse

My Genes