Vdac1 | voltage-dependent anion channel 1

GeneMGI:106919Synonyms: Vdac5

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased startle reflex	1 supporting dataset	Vdac1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.1x10^-8
impaired glucose tolerance	1 supporting dataset	Vdac1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	5.14x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Vdac1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Vdac1.

Associated images

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Histopathology

There is no histopathology data found for Vdac1.

IMPC related publications

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External links

No external links available for Vdac1.

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*Vdac1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Vdac1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Vdac1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Vdac1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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