Eif4a2 | eukaryotic translation initiation factor 4A2
Physiological systems
12 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological
10 No significant impact
12 Not tested
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal cholesterol homeostasis | 1 supporting dataset | Eif4a2em1(IMPC)J | homozygote | Early adult | 1.52x10-7 | ||
| increased thigmotaxis | 6 supporting datasets | Eif4a2em1(IMPC)J | homozygote | Early adult | 6.91x10-9 | ||
| hyperactivity | 3 supporting datasets | Eif4a2em1(IMPC)J | homozygote | Early adult | 1.18x10-10 | ||
| decreased blood urea nitrogen level | 1 supporting dataset | Eif4a2em1(IMPC)J | homozygote | Early adult | 3.8x10-5 | ||
| increased exploration in new environment | 1 supporting dataset | Eif4a2em1(IMPC)J | homozygote | Early adult | 1.5x10-6 | ||
| increased anxiety-related response | 1 supporting dataset | Eif4a2em1(IMPC)J | homozygote | Early adult | 9.3x10-6 | ||
| decreased locomotor activity | 2 supporting datasets | Eif4a2em1(IMPC)J | homozygote | Early adult | 4.27x10-9 | ||
| abnormal behavior | 1 supporting dataset | Eif4a2em1(IMPC)J | homozygote | Early adult | 4.84x10-5 |
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External links
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| Eif4a2em1(IMPC)J | Exon Deletion | | mouse |
| Eif4a2tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Eif4a2tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |