Efna4 | ephrin A4

GeneMGI:106643Synonyms: Epl4, EFL-4, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological Renal/urinary system

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



abnormal sleep behavior	1 supporting dataset	Efna4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.35x10^-6
abnormal cornea morphology	1 supporting dataset	Efna4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.61x10^-5
decreased circulating glucose level	1 supporting dataset	Efna4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.05x10^-5
impaired pupillary reflex	1 supporting dataset	Efna4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.41x10^-9
decreased urine creatinine level	1 supporting dataset	Efna4^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	6.2x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Efna4.

Associated images

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Histopathology

There is no histopathology data found for Efna4.

IMPC related publications

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External links

No external links available for Efna4.

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*Efna4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Efna4^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Efna4^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Efna4^{tm214483(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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