Baat | bile acid-Coenzyme A: amino acid N-acyltransferase

GeneMGI:106642Synonyms: taurine N-acyltransferase, BAT

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Vision/eye Hematopoietic system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating alkaline phosphatase level1 supporting datasetBaatem1(IMPC)MbphomozygoteEarly adult2.6x10-10 
abnormal lymph node morphology1 supporting datasetBaatem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased circulating cholesterol level1 supporting datasetBaatem1(IMPC)MbphomozygoteEarly adult2.11x10-9 
decreased circulating HDL cholesterol level1 supporting datasetBaatem1(IMPC)MbphomozygoteEarly adult1.12x10-8 
cataract1 supporting datasetBaatem1(IMPC)MbphomozygoteEarly adult3.22x10-5 
increased circulating triglyceride level1 supporting datasetBaatem1(IMPC)MbphomozygoteEarly adult1.31x10-6 
increased mean corpuscular volume1 supporting datasetBaatem1(IMPC)MbphomozygoteEarly adult6.62x10-6 
improved glucose tolerance1 supporting datasetBaatem1(IMPC)MbphomozygoteEarly adult8.58x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Baatem1(IMPC)MbpExon Deletionmouse
Baattm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Baattm99166(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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